The Look AHEAD Trial: Bone Loss at Four-Year Follow-Up in Type 2 Diabetes
Clinical Trial News Thursday, August 7th, 2014Diabetes Care July 21, 2014
OBJECTIVE To determine whether an intensive lifestyle intervention (ILI) designed to sustain weight loss and improve physical fitness in overweight or obese persons with type 2 diabetes was associated with bone loss after 4 years of follow-up.
RESEARCH DESIGN AND METHODS This randomized controlled trial of intensive weight loss compared an ILI with a diabetes support and education (DSE) group among 1,309 overweight or obese subjects. Bone mineral density was assessed at baseline and after 1 year and 4 years of intervention. Read more