Clinical Trial News
Thursday, September 19th, 2013
JAMA: 9/11/13 Importance The US federal government is spending billions of dollars in physician incentives to encourage the meaningful use of electronic health records (EHRs). Although the use of EHRs has potential to improve patient health outcomes, the existing evidence has been limited and inconsistent. Objective To examine the association between implementing a commercially available outpatient EHR […]
Clinical Trial News
Thursday, September 19th, 2013
Diabetes Care: September 11, 2013 Objective We previously reported that selective depletion of B-lymphocytes with rituximab, an anti-CD20 monoclonal antibody, slowed decline of beta-cell function in recent-onset type 1 diabetes mellitus (T1DM) at one year. Subjects were followed further to determine whether there was persistence of effect. Research Design and Methods Eighty-seven subjects (ages 8-40) were randomly assigned […]
Clinical Trial News
Thursday, September 19th, 2013
Ann Fam Med: September/October 2013 PURPOSE Cinnamon has been studied in randomized controlled trials (RCTs) for its glycemic-lowering effects, but studies have been small and show conflicting results. A prior meta-analysis did not show significant results, but several RCTs have been published since then. We conducted an updated systematic review and meta-analysis of RCTs evaluating cinnamon’s effect […]
Clinical Trial News
Thursday, September 19th, 2013
Diabetes Care: August 13, 2013 OBJECTIVE Transcription factor 7-like 2 (TCF7L2) polymorphisms are strongly associated with type 2 diabetes, but controversially with plasma lipids and cardiovascular disease. Interactions of the Mediterranean diet (MedDiet) on these associations are unknown. We investigated whether the TCF7L2-rs7903146 (C>T) polymorphism associations with type 2 diabetes, glucose, lipids, and cardiovascular disease incidence were modulated […]
News
Thursday, September 19th, 2013
Pophealthmetrics: September 18, 2013 Although diabetes is one of the most costly and rapidly increasing serious chronic diseases worldwide, the optimal mix of strategies to reduce diabetes prevalence has not been determined. Methods Using a dynamic model that incorporates national data on diabetes prevalence and incidence, migration, mortality rates, and intervention effectiveness, we project the effect […]
News
Thursday, September 19th, 2013
The Lancet Diabetes & Endocrinology: September 13, 2013 About 60% of patients with type 2 diabetes achieve remission after Roux-en-Y gastric bypass (RYGB) surgery. No accurate method is available to preoperatively predict the probability of remission. Our goal was to develop a way to predict probability of diabetes remission after RYGB surgery on the basis […]
News
Thursday, September 19th, 2013
Circulation Research: 9/13/13 Diabetes and obesity have emerged as global epidemics. At present more than 150 million individuals worldwide are living with diabetes and this number is expected to increase by 30% by 2015 and double to 300 million by 2025. In the US alone, there are 18.2 million diabetics (6.3% of the total population) and […]
News
Thursday, September 19th, 2013
Diabetes Care: September 11, 2013 Objective To evaluate the cost-effectiveness of a genetic testing policy for HNF1A, HNF4Aand GCK-MODY in a hypothetical cohort of type 2 diabetes patients 25-40 years old with a MODY prevalence of 2%. Research Design and Methods We used a simulation model of type 2 diabetes complications based on UKPDS data, modified to account for the natural […]
Minority Diabetes Reports
Thursday, September 12th, 2013
Diabetes Care: September 11, 2013 OBJECTIVE To examine racial differences in sleep duration and its relationship with diabetes. RESEARCH DESIGN AND METHODS We used data from a nationally representative sample of U.S. adults (n = 130,943) participating in the National Health Interview Survey from 2004 to 2011. Usual sleep duration was self-reported and categorized as <7 h (short), 7 […]
Minority Diabetes Reports
Thursday, September 12th, 2013
Diabetes: September 5, 2013 Variants in the CDH13 gene have been identified as determinants of blood levels of adiponectin, an insulin-sensitizing adipokine. However, their association with other metabolic risk factors remains unclear. We examined variants at CDH13 in relation to total and HMW adiponectin using data from a genome-wide association study performed in 2,434 Singaporean Chinese with replication in up […]
