Am J Clin Nutr, 16 December 2015 Background: In contrast with some epidemiologic evidence, our previous research showed that a 4-wk diet that was high in low-fat dairy reduced insulin sensitivity compared with the effect of a diet that was high in red meat. Objective: We investigated whether a dairy meal would produce a greater insulin response […]
Diabetes Prevention and Weight Loss with a Fully Automated Behavioral Intervention by Email, Web, and Mobile Phone: A Randomized Controlled Trial Among Persons with PrediabetesClinical Trial News Tuesday, February 9th, 2016
J Med Internet Res, 23 October 2015 Background: One-third of US adults, 86 million people, have prediabetes. Two-thirds of adults are overweight or obese and at risk for diabetes. Effective and affordable interventions are needed that can reach these 86 million, and others at high risk, to reduce their progression to diagnosed diabetes. Objective: The aim was […]
Diabetes Care, September 2015/p> Quality glucose information is a core prerequisite for successful diabetes management. It enables professionals and people with diabetes to make medically relevant decisions on therapy. Details of glucose profile information beyond HbA1c have been largely derived from self-monitoring of blood glucose (SMBG). Given the evidence base demonstrating the benefits of SMBG, its […]
Am J Clin Nutr, 29 July 2015 Background: Few well-controlled studies have comprehensively examined the effects of very-low-carbohydrate diets on type 2 diabetes (T2D). Objective: We compared the effects of a very-low-carbohydrate, high–unsaturated fat, low–saturated fat (LC) diet with a high-carbohydrate, low-fat (HC) diet on glycemic control and cardiovascular disease risk factors in T2D after 52 wk. … […]
Does Type 2 Diabetes Genetic Testing and Counseling Reduce Modifiable Risk Factors? A Randomized Controlled Trial of VeteransClinical Trial News Tuesday, February 9th, 2016
J Gen Intern Med, 16 April 2015 Objective We examined the clinical utility of supplementing type 2 diabetes mellitus (DM) risk counseling with DM genetic test results and counseling. … Conclusions Providing patients with genetic test results was not more effective in changing patient behavior to reduce the risk of DM compared to conventional risk counseling. Read more.
A Randomized Controlled Trial Comparing Telemedical and Standard Outpatient Monitoring of Diabetic Foot UlcersClinical Trial News, Clinical Trials, Clinical Trials Friday, August 21st, 2015
Diabetes Care 26 June 2015 OBJECTIVE The role of telemedical monitoring in diabetic foot ulcer care is still uncertain. Our aim was to compare telemedical and standard outpatient monitoring in the care of patients with diabetic foot ulcers in a randomized controlled trial.… CONCLUSIONS The findings of no significant difference regarding amputation and healing between […]
Metabolic Effects of Exercise Training Among Fitness Nonresponsive Patients With Type 2 Diabetes Mellitus: The HART-D StudyClinical Trial News, Clinical Trials, Clinical Trials Friday, August 21st, 2015
Diabetes Care, 17 June 2015 OBJECTIVE To evaluate the impact of exercise training (ET) on metabolic parameters among participants with type 2 diabetes mellitus (T2DM) who do not improve their cardiorespiratory fitness (CRF) with training.… CONCLUSIONS ET is associated with significant improvements in metabolic parameters irrespective of improvement in cardiorespiratory fitness. Read more.
Am J Clin Nutr, 25 March 2015 Background: Epidemiologic studies have linked high consumption of red and processed meat with risk of developing type 2 diabetes, whereas high dairy consumption has been associated with decreased risk, but interventions have been limited. Objective: We compared the effects on insulin sensitivity of consuming a diet high in […]
Pharmacokinetics and Pharmacodynamics of Insulin Glargine Given in the Evening as Compared With in the Morning in Type 2 DiabetesClinical Trial News, Clinical Trials, Clinical Trials Friday, August 21st, 2015
Diabetes Care, March 2015 OBJECTIVE To compare pharmacokinetics (PK) and pharmacodynamics (PD) of insulin glargine in type 2 diabetes mellitus (T2DM) after evening versus morning administration.… CONCLUSIONS The PD of insulin glargine differs depending on time of administration. With morning administration insulin activity is greater in the first 0–12 h, while with evening administration the […]
Canagliflozin Provides Durable Glycemic Improvements and Body Weight Reduction Over 104 Weeks Versus Glimepiride in Patients With Type 2 Diabetes on Metformin: A Randomized, Double-Blind, Phase 3 StudyClinical Trial News, Clinical Trials, Clinical Trials Friday, August 21st, 2015
Diabetes Care, 9 September 2014 OBJECTIVE To assess the efficacy/safety of canagliflozin, a sodium–glucose cotransporter 2 inhibitor, compared with glimepiride over 104 weeks in patients with type 2 diabetes inadequately controlled with metformin.… CONCLUSIONS Canagliflozin provided durable glycemic improvements compared with glimepiride and was generally well tolerated in patients with type 2 diabetes receiving background […]