Comparing Type 2 Diabetes, Prediabetes, and Their Associated Risk Factors in Asian Indians in India and in the U.S.: The CARRS and MASALA Studies

Diabetes Care, July2015

OBJECTIVE To assess the prevalence of diabetes and prediabetes and the associated risk factors in two Asian Indian populations living in different environments.

RESEARCH DESIGN AND METHODS We performed cross-sectional analyses, using representative samples of 2,305 Asian Indians aged 40–84 years living in Chennai, India, from the Centre for cArdiometabolic Risk Reduction in South-Asia study (CARRS) (2010–2011), and 757 Asian Indians aged 40–84 years living in the greater San Francisco and Chicago areas from the U.S. Mediators of Atherosclerosis in South Asians Living in America (MASALA) study (2010–2013). …

CONCLUSIONS These findings indicate possible changes in the relationship between migration and diabetes risk and highlight the growing burden of disease in urban India. Additionally, these results call for longitudinal studies to better identify the gene-environment-lifestyle exposures that underlie the elevated risk for type 2 diabetes development in Asian Indians. Read more.

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