Minority Diabetes Reports
Saturday, January 18th, 2014
Diabetes: January 2014 South Asians (SAs) develop type 2 diabetes at a younger age and lower BMI compared with Caucasians (Cs). The underlying cause is still poorly understood but might result from an innate inability to adapt to the Westernized diet. This study aimed to compare the metabolic adaptation to a high-fat, high-calorie (HFHC) diet between […]
Minority Diabetes Reports
Saturday, January 18th, 2014
Nature: December 25, 2013 Performing genetic studies in multiple human populations can identify disease risk alleles that are common in one population but rare in others1, with the potential to illuminate pathophysiology, health disparities, and the population genetic origins of disease alleles. Here we analysed 9.2 million single nucleotide polymorphisms (SNPs) in each of 8,214 Mexicans […]
Minority Diabetes Reports
Saturday, January 18th, 2014
Biomedcentral: December 23, 2013 Background There is strong evidence based on previous studies that ethnicity and socioeconomic status are important determinants of diversity in the occurrence of diabetes. However, the independent roles of socioeconomic status, country of birth and lifestyle factors in the occurrence of type 2 diabetes have not been clearly identified. This study investigated […]
Minority Diabetes Reports
Saturday, January 18th, 2014
Diabetes December 18, 2013 We previously showed that ethnicity modifies the association between adiposity and insulin resistance. We sought to determine whether differential body fat partitioning or abnormalities in muscle insulin signaling associated with higher levels of adiposity might underlie this observation. We measured insulin sensitivity index (ISI), %body fat, visceral (VAT) and subcutaneous (SAT) adipose […]
Clinical Trials
Saturday, January 18th, 2014
Annals: January 7, 2014 Background: Interventions promoting weight loss can reduce the incidence of type 2 diabetes mellitus. Whether dietary changes without calorie restriction also protect from diabetes has not been evaluated. Objective: To assess the efficacy of Mediterranean diets for the primary prevention of diabetes in the Prevención con Dieta Mediterránea trial, from October 2003 to December […]
Clinical Trial News
Friday, January 17th, 2014
Springer: January 2014 We compared two implementation approaches for a health literacy diabetes intervention designed for community health centers. METHODS A quasi-experimental, clinic-randomized evaluation was conducted at six community health centers from rural, suburban, and urban locations in Missouri between August 2008 and January 2010. In all, 486 adult patients with type 2 diabetes mellitus […]
Clinical Trial News
Friday, January 17th, 2014
Diabetes Care: January 2014 OBJECTIVE To evaluate whether intensive treatment (INT) with the goal of achieving blood glucose levels as close to the nondiabetic range as safely possible reduced the risk of onset and progression of diabetic retinopathy (DR) in subjects with type 1 diabetes (T1D) compared with conventional therapy (CON). RESEARCH DESIGN AND METHODS The Diabetes Control […]
Clinical Trial News
Friday, January 17th, 2014
Diabetes Care: October 29, 2013 Objective We examined the impact of intensive vs. conventional diabetes treatment upon menopause among women with type 1 diabetes in the Diabetes Control and Complications Trial (DCCT), a randomized controlled trial of intensive diabetes treatment, and its observational follow-up, the Epidemiology of Diabetes Interventions and Complications (EDIC) Study. Research Design and Methods In […]
Clinical Trials
Friday, January 17th, 2014
Diabetes Care: January 2014 OBJECTIVE Glucagon-like peptide 1 (GLP-1) is an incretin hormone that is released from the gastrointestinal tract. Treatment with GLP-1 analogs has proven to be of clinical use for patients with type 2 diabetes. Patients with type 1 diabetes, particularly those with residual β-cell function, may also respond to treatment, but the acute metabolic […]
News
Friday, January 17th, 2014
NEJM: 1/16/14 The relation between body weight and mortality among persons with type 2 diabetes remains unresolved, with some studies suggesting decreased mortality among overweight or obese persons as compared with normal-weight persons (an “obesity paradox”). METHODS We studied participants with incident diabetes from the Nurses’ Health Study (8970 participants) and Health Professionals Follow-up Study (2457 […]
