HLA class II genotyping of African American type 1 diabetes patients reveals associations unique to African haplotypes
Minority Diabetes Reports Wednesday, July 3rd, 2013Diabetes – June 25, 2013
HLA genotyping was performed on African American type 1 diabetes patients (n = 772) and controls (n = 1641), the largest study of African Americans and type 1 diabetes reported to date. Cases were from Children’s Hospital and Research Center Oakland and from existing collections (T1DGC, DCCT/EDIC, and GoKinD). Controls were from the T1DGC and from newborn bloodspot cards. The diversity of HLA DRB1-DQA1-DQB1 haplotypes and genotypes is far greater than that found in Europeans and European Americans. Read more
