Liver Fat has a Stronger Association with Risk Factors for Type 2 Diabetes in African-American Compared to Hispanic Adolescents
Minority Diabetes Reports Wednesday, July 24th, 2013The Journal of Clinical Endocrinology & Metabolism: July 19, 2013
Context: Although overweight and obese African-Americans (AA) have less visceral adipose tissue (VAT) and liver fat (LF) than Hispanics, they have a similar risk for type 2 diabetes (T2D).
Objective: We examined ethnic differences in the association between VAT and LF with risk factors for T2D to help explain this paradox.
Design: Cross-sectional study.
Setting: Primary care.
Subjects: Overweight and obese AA (n=131; 15.5±3.3 years) and Hispanic adolescents (n=227; 14.7±3.0 years).
Main Outcome Measures: Insulin sensitivity (SI), acute insulin response (AIR), and disposition index (DI) by FSIVGTT and minimal modeling. Read More