Metabolic Effects of Bariatric Surgery in Patients With Moderate Obesity and Type 2 Diabetes

Clinical Trials Thursday, February 28th, 2013

Diabetes Care February 25, 2013

OBJECTIVE To evaluate the effects of two bariatric procedures versus intensive medical therapy (IMT) on β-cell function and body composition.

RESEARCH DESIGN AND METHODS A prospective, randomized, controlled trial of 60 subjects with uncontrolled type 2 diabetes (HbA1c 9.7 ± 1%) and moderate obesity (BMI 36 ± 2 kg/m2) randomized to IMT alone, IMT plus Roux-en-Y gastric bypass, or IMT plus sleeve gastrectomy. Assessment of β-cell function (mixed meal tolerance testing) and body composition were performed at baseline and 12 and 24 months. Read more

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