Sex hormone binding globulin and sex steroids among premenopausal women in the Diabetes Prevention Program
Minority Diabetes Reports Thursday, May 30th, 2013JCEM: May 24, 2013
Context It is unknown whether intensive lifestyle modification (ILS) or metformin change sex steroids among premenopausal women without a history of polycystic ovarian syndrome (PCOS).
Objectives To examine one-year intervention impact upon sex steroids (estradiol, testosterone, dehydroepiandrosterone, and androstenedione [A4]) and sex hormone binding globulin (SHBG) and differences by race/ethnicity
Participants A subgroup of Diabetes Prevention Program (DPP) participants who were premenopausal, not using estrogen, without a history of PCOS or irregular menses, and who reported non-Hispanic white (NHW), Hispanic, or African-American race/ethnicity (n=301). Read more