Short Leukocyte Telomere Length Predicts

Minority Diabetes Reports Thursday, August 22nd, 2013

Diabetes: August 15, 2013

Risk of Diabetes in American Indians: The Strong Heart Family Study

 

Telomeres play a central role in cellular aging and shorter telomere length has been associated with age-related disorders including diabetes. However, a causal link between telomere shortening and diabetes risk has not been established. In a well-characterized longitudinal cohort of American Indians participating in the Strong Heart Family Study, we examined whether leukocyte telomere length (LTL) at baseline predicts incident diabetes independent of known diabetes risk factors. Among 2,328 participants free of diabetes at baseline, 292 subjects developed diabetes during an average 5.5 years of follow-up.  Read more

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