Study finds that triple therapy corrects two core defects in type 2 diabetes
Clinical Trials Thursday, June 27th, 2013News Medical June 25, 2013
Therapy produced stable glucose and hemoglobin A1C readings, and weight loss
Patients with type 2 diabetes fare significantly better if they are started on three medications at the time of diagnosis than if they are prescribed a single drug and have other therapies added later, a San Antonio researcher said June 22 at the 73rd Scientific Sessions of the American Diabetes Association in Chicago. The findings, from a study funded by the association, could revise the way physicians manage the endocrine disease.
Comparison
UT Medicine San Antonio physician Ralph DeFronzo, M.D., chief of the Diabetes Division in the School of Medicine at The University of Texas Health Science Center at San Antonio, presented two-year results from 134 participants studied at University Health System’s Texas Diabetes Institute. Half of the subjects received the triple-therapy regimen while the other half received the conventional regimen recommended by the ADA. The standard regimen begins with a single agent (metformin), adds another (sulfonylurea) when the first agent fails, and then adds insulin injections as needed to control blood glucose after the second agent fails. Read more
