The Influence of Hyperglycemia on the Therapeutic Effect of Exercise on Glycemic Control in Patients With Type 2 Diabetes Mellitus

Clinical Trials Wednesday, July 3rd, 2013

JAMA Intern Med. – July 1, 2013

Randomized clinical trials show that aerobic exercise training improves glycemic control in patients with type 2 diabetes mellitus (T2DM).1 However, interindividual variability is large.2 This may be explained by genetic variability,3 but ambient hyperglycemia4 and pancreatic β-cell function5 may also contribute. We examined whether changes in glycemic control following a 12- to 16-week aerobic exercise training intervention were influenced by the pretraining glycemic state in 105 individuals with impaired glucose tolerance or T2DM. Read More

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