Diabetes Care: March 1, 2013 Type 2 diabetes is a serious, costly, and potentially preventable public health problem in the U.S., and both the prevalence and incidence of diabetes have increased rapidly since the mid-1990s (1). Currently, >7% of adults in the U.S. have been diagnosed with type 2 diabetes, and diabetes-related care accounts for 11% […]
Diabetes Care: March 1, 2013 Relative to individuals with European ancestry, presence and severity of calcified atherosclerotic plaque (CP) are markedly lower in individuals with African ancestry (1,2). Factors potentially contributing to the ethnic variation in susceptibility to atherosclerosis include different relationships between CP and serum 25 hydroxyvitamin D concentrations and pericardial adipose tissue volumes in […]
The Diabetes Educator: February 25, 2013 Purpose The purpose of this article is to describe methods used to recruit and retain high-risk, Spanish-speaking adults of Mexican origin in a randomized clinical trial that adapts Diabetes Prevention Program (DPP) content into a community-based, culturally tailored intervention. Methods Multiple passive and active recruitment strategies were analyzed for effectiveness in reaching […]
he Diabetes Educator: February 22, 2013 Purpose The purpose of this study was to examine the implementation, use, and sustainability of a computerized touch-screen diabetes education kiosk (Diosk) designed to provide “on-demand” education in a predominantly Latino community in South Texas. Methods A pilot study was conducted to examine the implementation, use, and sustainability of the Diosk in […]
The Diabetes Educator: February 20, 2013 Purpose To examine challenges in diabetes self-management among Korean Americans to guide clinicians in providing culturally appropriate and population-targeted diabetes care. Methods Five focus groups with 23 Korean Americans with type 2 diabetes, 30 to 75 years of age, were conducted. Open-ended questions were presented focusing on previous experiences in living with […]
Diabetes Care February 25, 2013 OBJECTIVE To evaluate the effects of two bariatric procedures versus intensive medical therapy (IMT) on β-cell function and body composition. RESEARCH DESIGN AND METHODS A prospective, randomized, controlled trial of 60 subjects with uncontrolled type 2 diabetes (HbA1c 9.7 ± 1%) and moderate obesity (BMI 36 ± 2 kg/m2) randomized to IMT alone, IMT […]
Diabetes Care: February 22, 2013 OBJECTIVE Effective and easily implemented insulin regimens are needed to facilitate hospital glycemic control in general medical and surgical patients with type 2 diabetes (T2D). RESEARCH DESIGN AND METHODS This multicenter trial randomized 375 patients with T2D treated with diet, oral antidiabetic agents, or low-dose insulin (≤0.4 units/kg/day) to receive a basal bolus […]
Diabetes Care: February 22, 2013 OBJECTIVE The effect of therapeutic strategies on cardiovascular (CV) disease can be evaluated by monitoring changes in CV risk biomarkers. This study investigated the effect of a structured self-monitoring of blood glucose (SMBG) protocol and the resulting improvements in glycemic control on changes in high-sensitivity C-reactive protein (hs-CRP) in insulin-naïve patients with […]
BMC Medicine: February 20, 2013 Background Management of type 2 diabetes with metformin often does not provide adequate glycemic control, thereby necessitating add-on treatment. In a 24-week clinical trial, dapagliflozin, an investigational sodium glucose cotransporter 2 inhibitor, improved glycemic control in patients inadequately controlled with metformin. The present study is an extension that was undertaken to […]
Diabetes Care: October 15, 2012 OBJECTIVE Patients with the metabolic syndrome (MetS) have impaired insulin-induced enhancement of vasodilator responses. The incretin hormone glucagon-like peptide 1 (GLP-1), beyond its effects on blood glucose, has beneficial actions on vascular function. This study, therefore, aimed to assess whether GLP-1 affects insulin-stimulated vasodilator reactivity in patients with the MetS. RESEARCH DESIGN […]
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