Clinical Trials
Thursday, April 18th, 2013
The Diabetes Educator: April 15, 2013 Purpose The purpose of this study is to evaluate the effectiveness of a nutrition-based shared medical appointment (SMA) intervention in the treatment of prediabetes compared to the individualized counseling standard of care. Methods A randomized controlled trial design comparing health outcomes in patients with prediabetes attending either an individualized counseling (control group) […]
Clinical Trials
Thursday, April 18th, 2013
JCEM: April 12, 2013 Context: The stepwise hyperglycemic clamp procedure (SHCP) is the gold standard for measuring the renal threshold for glucose excretion (RTG), but its use is limited to small studies in specialized laboratories. Objective: The objective of the study was to validate a new method for determining RTG using data obtained during a mixed-meal tolerance test […]
Clinical Trials
Thursday, April 18th, 2013
ADA Diabetes Care: April 11, 2013 OBJECTIVE To assess glucose-lowering mechanisms of sitagliptin (S), metformin (M), and the two combined (M+S). RESEARCH DESIGN AND METHODS We randomized 16 patients with type 2 diabetes mellitus (T2DM) to four 6-week treatments with placebo (P), M, S, and M+S. After each period, subjects received a 6-h meal tolerance test (MTT) with [14C]glucose […]
Clinical Trials
Thursday, April 18th, 2013
ADA Diabetes Care: April 11, 2013 OBJECTIVE The purpose of this study was to determine the efficacy of two internet-based psycho-educational programs designed to improve outcomes for youth with type 1 diabetes transitioning to adolescence. RESEARCH DESIGN AND METHODS The study was a multisite clinical trial of 320 youth (age 11–14 years; 37% minority; 55% female) randomized to one […]
Clinical Trials
Thursday, April 18th, 2013
European Medicines Agency: April 9, 2013 Almost 62% of the patients in pivotal trials submitted in marketing-authorisation applications (MAAs) to the European Medicines Agency between January 2005 and December 2011 were recruited outside of the European Economic Area (EEA) and Switzerland, according to an analysis performed by the Agency. The report on clinical trials submitted in […]
News
Thursday, April 18th, 2013
JCEM: April 15, 2013 Objective: To review the evidence about the impact of hypoglycemia on patients with diabetes that has become available since the past reviews of this subject by the American Diabetes Association and The Endocrine Society and to provide guidance about how this new information should be incorporated into clinical practice. Participants: Five members of […]
News
Thursday, April 18th, 2013
The Diabetes Educator: April 15, 2013 Purpose The purpose of this study was to examine reports of diabetes learning needs by youth with type 2 diabetes and their family support person (FSP) and to examine correlations of these perceptions with demographic variables. Methods Data were analyzed from the Participant Needs Assessment (PNA), a routinely self-administered questionnaire designed to […]
News
Thursday, April 18th, 2013
PLOS One: April 10, 2013 Introduction Skin and soft tissue infections (SSTIs) are common infections occurring in ambulatory and inpatient settings. The extent of complications associated with these infections by diabetes status is not well established. Methods Using a very large repository database, we examined medical and pharmacy claims of individuals aged 0–64 between 2005 […]
News
Thursday, April 18th, 2013
Arteriosclerosis, Thrombosis, and Vascular Biology: April 4, 2013 Objective—To test whether equivalent energy expenditure by moderate-intensity (eg, walking) and vigorous-intensity exercise (eg, running) provides equivalent health benefits. Approach and Results—We used the National Runners’ (n=33 060) and Walkers’ (n=15 945) Health Study cohorts to examine the effect of differences in exercise mode and thereby exercise intensity […]
News
Thursday, April 18th, 2013
ADA Diabetes Care: February 19, 2013 OBJECTIVE Laboratory studies suggest that exposure to methylmercury at a level similar to those found in fish may induce pancreatic islet β-cell dysfunction. Few, if any, human studies have examined the association between mercury exposure and diabetes incidence. We examined whether toenail mercury levels are associated with incidence of diabetes in a […]
