Minority Diabetes Reports
Sunday, April 14th, 2013
ADA Diabetes: April 4, 2013 Prepubertal African American (AA) youth compared with their Caucasian (C) peers have higher insulin secretion which correlates positively with free fatty acid (FFA) concentration. In our continued efforts to explain the racial disparity in insulinemia, and because FFAs modulate insulin secretion, we hypothesized that AA youth would have a greater response to […]
Minority Diabetes Reports
Sunday, April 14th, 2013
CDC: March 28, 2013 Introduction The Indo-Guyanese population is the largest immigrant minority population in Schenectady, New York. A clinic-based study in Schenectady and surveillance reports from Guyana found high diabetes prevalence and mortality among Guyanese of Indian descent. No community-based study has focused on diabetes among Indo-Guyanese immigrants in the United States. We sought information […]
Clinical Trials
Sunday, April 14th, 2013
ADA Diabetes: April 8, 2013 We investigated: 1) the ability of purified glargine (GLA), metabolites 1 (M1) and 2 (M2), IGF-I, and NPH insulin to activate the insulin receptor (IR)-A and IR-B and IGF-I receptor (IGF-IR) in vitro; 2) plasma concentrations of GLA, M1, and M2 during long-term insulin therapy in type 2 diabetic patients; and 3) IR-A and IR-B […]
Clinical Trials
Sunday, April 14th, 2013
ADA Diabetes Care: April 5, 2013 OBJECTIVE When oral therapy for type 2 diabetes is ineffective, adding basal insulin improves glycemic control. However, when glycated hemoglobin (HbA1c) remains elevated because of postprandial hyperglycemia, the next therapeutic step is controversial. We examined the efficacy and safety of lixisenatide in patients with HbA1c still elevated after initiation of insulin glargine. RESEARCH […]
Clinical Trials
Sunday, April 14th, 2013
ADA Diabetes Care: April 5, 2013 OBJECTIVE To evaluate the efficacy and safety of canagliflozin, a sodium glucose cotransporter 2 inhibitor, compared with sitagliptin in subjects with type 2 diabetes inadequately controlled with metformin plus sulfonylurea. RESEARCH DESIGN AND METHODS In this 52-week, randomized, double-blind, active-controlled, phase 3 study, subjects using stable metformin plus sulfonylurea (N = 755) received canagliflozin […]
Clinical Trials
Sunday, April 14th, 2013
ADA Diabetes Care: April 5, 2013 OBJECTIVES To evaluate the effects of insulin glargine and n-3 polyunsaturated fatty acid (n-3FA) supplements on carotid intima-media thickness (CIMT). RESEARCH DESIGN AND METHODS We enrolled 1,184 people with cardiovascular (CV) disease and/or CV risk factors plus impaired fasting glucose, impaired glucose tolerance, or early type 2 diabetes in a randomized multicenter 2 […]
Clinical Trials
Sunday, April 14th, 2013
Diabetologia: April 3, 2013 Abstract Aims/hypothesis Clinical trials assessing interventions for treating and preventing diabetes mellitus and its complica- tions are needed to inform evidence-based practice. To examine whether current studies adequately address these needs, we conducted a descriptive analysis of diabetes- related trials registered with ClinicalTrials.gov from 2007 to 2010. Methods From a dataset […]
News
Sunday, April 14th, 2013
FDA: April 8, 2013 Product(s): Animas 2020 Insulin Infusion Pumps Lot numbers: All lots manufactured from March 1, 2012 to November 30, 2012. Manufacturing and Distribution Dates: The affected products were manufactured from March 1, 2012 to November 30, 2012 and distributed from March 1, 2012 to September 30, 2012. Use: The Animas 2020 Insulin Pumps are […]
News
Sunday, April 14th, 2013
ADA Diabetes Care: April 5, 2013 OBJECTIVE To compare risk of all-cause mortality, cardiovascular disease (CVD) mortality, acute myocardial infarction (AMI) mortality, stroke mortality, and hospitalizations for males and females with and without diabetes and those with diabetes diagnosed early and late. RESEARCH DESIGN AND METHODS Population-based retrospective cohort study including 73,783 individuals aged 25 years or older in […]
News
Sunday, April 14th, 2013
ADA Diabetes Care: April 5, 2013 OBJECTIVE To compare clinical profile of long-term survivors and nonsurvivors with type 2 diabetes (T2DM). RESEARCH DESIGN AND METHODS After conducting a retrospective survey of >200,000 case records, we identified T2DM survivors (>40 years of duration) and age at diagnosis and sex-matched T2DM nonsurvivors. Prevalence of complications and causes of death were analyzed. […]
