Clinical Trial News
Tuesday, June 24th, 2014
Diabetes Care June 2014 OBJECTIVE We examined the effects of an intensive lifestyle intervention (ILI), compared with a diabetes support and education (DSE) control intervention, on long-term changes in depression symptoms, antidepressant medication (ADM) use, and health-related quality of life (HRQoL) in overweight/obese individuals with type 2 diabetes. RESEARCH DESIGN AND METHODS Look AHEAD was a multisite randomized […]
Clinical Trial News
Tuesday, June 24th, 2014
Springer: June 2014 Aims/hypothesis The estimation of effect size in clinical trials commonly disregards recurrent outcomes. We investigated the effectiveness of a complex intervention on recurrent outcomes in patients with type 2 diabetes. Methods In the Diabetes Care in General Practice (DCGP) randomised controlled trial, 1,381 patients newly diagnosed with type 2 diabetes were randomised to […]
Clinical Trial News
Tuesday, June 24th, 2014
Diabetes Care: May 30, 2014 Objective To compare efficacy and safety of dulaglutide, a once weekly glucagon-like peptide1 receptor agonist, to placebo and exenatide in type 2 diabetes patients. Primary objective was superiority of dulaglutide 1.5 mg versus placebo in HbA1cchange at 26 weeks. Research Design and Methods This 52-week, multicenter, parallel-arm study (primary endpoint: 26 weeks) randomized […]
Clinical Trial News
Tuesday, June 24th, 2014
Diabetes Care May 19, 2014 OBJECTIVE Compare the efficacy and safety of monotherapy with dulaglutide, a once-weekly GLP-1 receptor agonist, to metformin-treated patients with type 2 diabetes. The primary objective compared dulaglutide 1.5 mg and metformin on change from baseline glycosylated hemoglobin A1c (HbA1c) at 26 weeks. RESEARCH DESIGN AND METHODS This 52-week double-blind study randomized patients to subcutaneous […]
News
Monday, June 9th, 2014
JAMA: May 7, 2014 mportance Despite concern about an “epidemic,” there are limited data on trends in prevalence of either type 1 or type 2 diabetes across US race and ethnic groups. Objective To estimate changes in the prevalence of type 1 and type 2 diabetes in US youth, by sex, age, and race/ethnicity between 2001 and 2009. Design, […]
News
Monday, June 9th, 2014
Tamhsc.edu: May 1, 2014 America is growing older and wider. At the same time baby boomers (the population born between 1946 and 1964) are celebrating their 65thbirthdays, obesity rates in the United States are skyrocketing. Seventy-five percent of Americans are currently living beyond the age of 65, which is great news. But more than one-third of […]
News
Monday, June 9th, 2014
Am J Clin Nutr: July 2014 Background: Epidemiologic evidence for the relation between carbohydrate quality and risk of type 2 diabetes (T2D) has been mixed. Objective: We prospectively examined the association of dietary glycemic index (GI) and glycemic load (GL) with T2D risk. Read More
News
Monday, June 9th, 2014
Springer: 4/26/14 Aims/hypothesis Coffee and tea consumption has been associated with a lower type 2 diabetes risk but little is known about how changes in coffee and tea consumption influence subsequent type 2 diabetes risk. We examined the associations between 4 year changes in coffee and tea consumption and risk of type 2 diabetes in the subsequent […]
News
Monday, June 9th, 2014
Clinical Diabetes: April 2014 This article describes available insulin products and published guidelines to aid clinicians in making treatment decisions for insulin-dependent patients with type 2 diabetes. It establishes the need for a thorough evaluation of the literature regarding ambulatory insulin dosing to further inform providers who manage insulin therapy for patients with type 2 diabetes. […]
News
Monday, June 9th, 2014
Diabetes Care: May 2014 OBJECTIVE Suboptimal adherence to diabetes medications is prevalent and associated with unfavorable health outcomes, but it remains unclear what intervention content is necessary to effectively promote medication adherence in diabetes. In other disease contexts, the Information–Motivation–Behavioral skills (IMB) model has effectively explained and promoted medication adherence and thus may have utility in explaining […]