Antipsychotics and the Risk of Type 2 Diabetes Mellitus in Children and Youth

JAMA: August 21, 2013 Importance   The increased prescribing of antipsychotics for children and youth has heightened concerns that this practice increases the risk of type 2 diabetes mellitus. Objective   To compare the risk of type 2 diabetes in children and youth 6 to 24 years of age for recent initiators of antipsychotic drugs vs propensity score–matched controls who had […]

Association of Depression With Accelerated Cognitive Decline Among Patients With Type 2 Diabetes in the ACCORD-MIND Trial

JAMA: 8/14/13 Importance   Depression has been identified as a risk factor for dementia among patients with type 2 diabetes mellitus but the cognitive domains and patient groups most affected have not been identified. Objective   To determine whether comorbid depression in patients with type 2 diabetes accelerates cognitive decline. Design   A 40-month cohort study of participants in the Action […]

Dairy products and the risk of type 2 diabetes: a systematic review and dose-response meta-analysis of cohort studies1,2,3

Ajcn: 8/14/13 Background: The association between intake of dairy products and the risk of type 2 diabetes has been investigated in several studies, but the evidence is not conclusive. Objective: We conducted an updated systematic review and dose-response meta-analysis of dairy product intake and the risk of type 2 diabetes. Design: We searched the PubMed database for […]

Investigation into the Value of Trained Glycaemia Alert Dogs to Clients with Type I Diabetes

PLOS: 8/7/13 Previous studies have suggested that some pet dogs respond to their owners’ hypoglycaemic state. Here, we show that trained glycaemia alert dogs placed with clients living with diabetes afford significant improvements to owner well-being. We investigated whether trained dogs reliably respond to their owners’ hypoglycaemic state, and whether owners experience facilitated tightened glycaemic control, and wider […]

Non-Traditional Risk Factors are Important Contributors to the Racial Disparity in Diabetes Risk: The Atherosclerosis Risk in Communities Study

Journal of General Internal Medicine: link.springer: August 2013   Traditional risk factors, particularly obesity, do not completely explain the excess risk of diabetes among African Americans compared to whites. OBJECTIVE We sought to quantify the impact of recently identified, non-traditional risk factors on the racial disparity in diabetes risk. DESIGN Prospective cohort study. PARTICIPANTS We analyzed data […]

Short Leukocyte Telomere Length Predicts

Diabetes: August 15, 2013 Risk of Diabetes in American Indians: The Strong Heart Family Study   Telomeres play a central role in cellular aging and shorter telomere length has been associated with age-related disorders including diabetes. However, a causal link between telomere shortening and diabetes risk has not been established. In a well-characterized longitudinal cohort of […]

Missing the Mark With Latina Women With Type 2 Diabetes

The Diabetes Educator: July 29, 2013 Implications for Educators   Purpose The purpose of this qualitative study was to explore nutritional behaviors and attitudes among Latino women with type 2 diabetes. Methods Women over 18 years old and previously diagnosed with type 2 diabetes were recruited to participate in semi-structured qualitative interviews in their homes in Los Angeles, […]

Screening for diabetes: what do the results of the ADDITION trial mean for clinical practice?

Futuremedicine: 8/19/13 SUMMARY The main ADDITION study was planned as a screening study followed by a randomized, intervention study comparing routine treatment with more intensive treatment in people with screen-detected diabetes. The stepwise screening programs had low yield, but for each person with diabetes identified, another two at high risk of diabetes and six at high risk […]

Consumption of a Diet Low in Advanced Glycation Endproducts for 4 weeks Improves Insulin Sensitivity in Overweight Women

Diabetes Care: August 19, 2013 Objective High heat cooking of food induces formation of advanced glycation endproducts (AGEs), which are thought to impair glucose metabolism in type 2 diabetic patients. High intake of fructose might additionally affect endogenous formation of AGEs. This parallel intervention study investigated whether addition of fructose or cooking methods influencing the AGE content […]

Stratified Patient-Centered Care in Type 2 Diabetes

A cluster-randomized, controlled clinical trial of effectiveness and cost-effectiveness Diabetes Care: August 15, 2013 OBJECTIVE Diabetes treatment should be effective and cost-effective. HbA1c-associated complications are costly. Would patient-centered care be more (cost-) effective if it was targeted to patients within specific HbA1c ranges? RESEARCH DESIGN AND METHODS This prospective, cluster-randomized, controlled trial involved 13 hospitals (clusters) in the Netherlands […]

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