Clinical Trial News
Wednesday, July 16th, 2014
Springer: August 2014 Abstract Aims/hypothesis The aim of the study was to compare the effect of six (A6 regimen) vs two meals a day, breakfast and lunch (B2 regimen), on body weight, hepatic fat content (HFC), insulin resistance and beta cell function. Methods In a randomised, open, crossover, single-centre study (conducted in Prague, Czech Republic), […]
Clinical Trial News
Wednesday, July 16th, 2014
Springer: July 2014 For many years, the randomised controlled clinical trial (RCT) has been the gold standard for evaluating the efficacy, tolerability and safety of drugs. The modern framework for RCTs was developed in the mid-20th century through the leadership of the UK Medical Research Council and the US National Institutes of Health in collaboration with […]
Clinical Trial News
Wednesday, July 16th, 2014
Springer: July 2014 Abstract Aims/hypothesis The aim of this study was to investigate whether small doses of intense exercise before each main meal (‘exercise snacks’) would result in better blood glucose control than a single bout of prolonged, continuous, moderate-intensity exercise in individuals with insulin resistance. Methods Nine individuals completed three exercise interventions in randomised […]
Clinical Trial News
Wednesday, July 16th, 2014
Springer: July 2014 Aims/hypothesis The aim of this study was to assess whether or not a theory-based behaviour change intervention delivered by trained and quality-assured lifestyle facilitators can achieve and maintain improvements in physical activity, dietary change, medication adherence and smoking cessation in people with recently diagnosed type 2 diabetes. Methods An explanatory randomised controlled […]
Clinical Trial News
Wednesday, July 16th, 2014
Cambridge: 4/30/14 Abstract The present meta-analysis of randomised controlled trials (RCT) aimed to investigate the effect of oat intake on glycaemic control and insulin sensitivity. A literature search was carried out in PubMed, ScienceDirect Online and The Cochrane Library (up to October 2013) for RCT that assessed the effect of oat intake on glucose control […]
Minority Diabetes Reports, Minority Diabetes Reports
Saturday, July 5th, 2014
Diabetes Care June 29, 2014 OBJECTIVE To compare the relationship between adiposity and prevalent diabetes across ethnic groups in the UK Biobank cohort and to derive ethnic-specific obesity cutoffs that equate to those developed on white populations in terms of diabetes prevalence. RESEARCH DESIGN AND METHODS UK Biobank recruited 502,682 U.K. residents aged 40–69 years. We used baseline […]
Minority Diabetes Reports, Minority Diabetes Reports
Saturday, July 5th, 2014
Diabetes Care June 26, 2014 OBJECTIVE To determine whether dietary patterns associated with food insecurity are associated with poor longitudinal glycemic control. RESEARCH DESIGN AND METHODS In a prospective, population-based, longitudinal cohort study, we ascertained food security (Food Security Survey Module), dietary pattern (Healthy Eating Index 2005 [HEI 2005]), and hemoglobin A1c (HbA1c) in Puerto Rican adults aged 45–75 […]
Minority Diabetes Reports, Minority Diabetes Reports
Saturday, July 5th, 2014
Wiley: 19 JUN 2014 Type 2 diabetes is considered a public health crisis, particularly among people of Mexican descent in the United States. Clinical approaches to diabetes management increasingly emphasize self-care, which places responsibility for illness on individuals and mandates self-regulation. Using narrative and free-list data from a two-phase study of low-income first- and second-generation […]
Minority Diabetes Reports, Minority Diabetes Reports
Saturday, July 5th, 2014
The Journal of Clinical Endocrinology & Metabolism: June 12, 2014 Abstract Context: Metformin is considered first-line treatment for type 2 diabetes mellitus. However, little is known about its effects in African American individuals. Objective: The objective of the study was to assess whether metformin’s effect on glycemic control differs by race-ethnicity Design: Electronic health records were […]
Clinical Trial News
Saturday, July 5th, 2014
Journal of General Internal Medicine/Springer: July 2014 INTRODUCTION Previous work has indicated that for patients with diabetes, there is value in understanding glycemic control. Despite these findings, patient understanding of the hemoglobin A1C value (A1C) is notably poor. In this study, we test the effect of two alternative communication formats of the A1C on improving […]